Multiple Sclerosis Research

Dr. Carl Asche, Director of the Center for Outcomes Research (COR) at the University of Illinois College of Medicine at Peoria (UICOMP) and his team perform economic evaluation and statistical analysis on a range of Multiple Sclerosis (MS) health care topics and activities funded by the Central Illinois MS Council. One example has been the development of an integrated MS Flowsheet Registry designed to provide a complete picture of the MS patient. COR partnered up on the project with the OSF JUMP Simulation Center and the OSF HealthCare Illinois Neurological Institute (INI) MS Center. COR has also worked in conjunction with the OSF HealthCare INI MS Center and the Central Illinois MS Council over the past three years to help organize a local research group around MS – the first of its kind in the U.S. devoted to MS. To date, they have secured three “Pipeline to Proposal” awards from Washington, D.C.-based Patient-Centered Outcomes Research Institute (PCORI) and now are seeking additional funding for a multi-year study evaluate yoga, treadmill exercise and aqua size (exercise within a swimming pool) as beneficial forms of therapy for MS.

The Center for Outcomes research is committed to collaborating in the improved health of multiple sclerosis patients. We recently completed the Tier III Patient Centered Outcomes Research Institute (PCORI) Award. In this project, people with multiple sclerosis discussed and prioritized research areas of greatest importance, connecting them with research and medical professionals with whom to collaborate.

We have applied for the Patient Centered Outcomes Research Institute (PCORI) Award where we will answer the question: Which exercise program is better for people with multiple sclerosis? Treadmill, Aquatic, or Yoga? Patients and researchers will lead this project. Partners include: Illinois Neurological Institute, Illinois State University, Jump Simulation and Education Center, and Center for Outcomes Research and Department of Medicine at the University of Illinois College of Medicine Peoria.

Newsletters

Event Materials

Sept. 19, 2015

March 1, 2016

Papers Published in Peer-Reviewed Journals

  1. Ren J, Ni H, Kim M, Cooley KL, Asche CV. Allergies, antibiotics use, and multiple sclerosis. Curr Med Res Opin. (accepted 5/2017).
  2. Valenzuela RM, Cooley KL, Paris BL, Gonia L, Taylor AJ, Asche CV. Comorbidities of multiple sclerosis patients treated at the Illinois Neurological Institute (INI) Multiple Sclerosis Center. Journal of Multiple Sclerosis & Neuroimmunology. 2016; 3(1): 1024 [E-pub].
  3. Cooley KL, Paris BL, Asche CV, Valenzuela R. Development of an Integrated Multiple Sclerosis Flowsheet Registry to Bridge the Gap between Electronic Health Record Functionality and Clinical Information Needs. Austin J Mult Scler & Neuroimmunol. 2015; 2(4): 1023.
  4. Asche CV, Corrol VS, Maloni HW. Economic Issues in MS Management. Counseling Points. Enhancing Patient Communication for the Multiple Sclerosis Nurse. Fall 2011 issue (Volume 1, Number 3).
  5. Asche CV, Singer ME, Jhaveri M, Chung H, Miller A. All-Cause Health Care Utilization and Costs Associated with Newly Diagnosed Multiple Sclerosis in the United States. J Manag Care Pharm. 2010 Nov-Dec;16(9):703-12. PMID: 21067256
  6. Asche CV, Ho E, Chan B, Coyte PC. Economic Consequences of Multiple Sclerosis for Canadians. Acta Neurologica Scandinavica, 955, 268-274, 1997. PMID: 9188900

Abstracts Presented/Published

  1. Cooley KL, Valenzuela RM, Garwacki DJ, Wankel K Ren J, Asche CV. Development of a multiple sclerosis registry to bridge the gap between electronic health record functionality and clinical information needs: A next generation MS documentation system. Annual Meeting of the Consortium of Multiple Sclerosis Centers, May 24-27, 2017, New Orleans, Louisiana (Poster Presentation).
  2. Cooley KL, Asche CV, Paris BL, Kim M, Ren J, Garwacki D, Kattah JC, Wei Y, Gonia L, Valenzuela R. A Multiple Sclerosis Flowsheet Registry Integrated with the Electronic Health Record to Provide Comprehensive Care and Local Research Opportunities. Consortium of Multiple Sclerosis Centers Annual Meeting (CMSC), June 1-4, 2016, National Harbor, Maryland (Poster Presentation).
  3. Cooley KL, Asche CV, Paris BL, Kim M, Ren J, Garwacki D, Kattah JC, Wei Y, Gonia L, Valenzuela R. Integrating a database registry within an EHR for MS management. Association of Clinical Research Professionals (ACRP), April 16-19, 2016, Atlanta, Georgia (Poster Presentation).
  4. Asche CV, Cooley KL. UICOMP Department of Neurosciences Grand Rounds. Development of an Integrated Multiple Sclerosis Flowsheet Registry to Provide a Complete Clinical Picture of the Patient. March 18, 2016 (Oral Presentation).
  5. Asche CV. 2015 Research Update. 9th Annual Regional Research Symposium. National Multiple Sclerosis Society, Greater Illinois Chapter. Embassy Suites Hotel and Riverfront Conference Center, East Peoria, IL. August 29, 2015 (Oral Presentation).
  6. Valenzuela RM, Gonia LM, Taylor AJ, Wankel K, Cooley KL, Parry VL, Asche CV. Demographic and clinical characteristics of Multiple Sclerosis (MS) patients treated at the Illinois Neurological Institute (INI) MS Center. OSF 2014 Annual Research Symposium, Peoria, IL, May 6, 2014 (Poster Presentation).
  7. Asche CV. The Economics of MS in the US. MS Care Health Policy Implications: Economics of MS in the USA for the Fourth Collaborative Meeting of the Consortium of Multiple Sclerosis Centers (CMSC) and the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Hilton San Diego Bay front, San Diego, CA (Educational Symposium presented on June 2, 2012).
  8. Singer M, Asche CV, Chung H, Jhaveri M, Miller A. Cost and resource use related to newly diagnosed multiple sclerosis: Real-world data from a large US claims database. 12th Annual European Meeting of the ISPOR, Paris (Poster Presentation). Abstract published in: Value in Health 2008.
  9. Asche CV, Singer ME, Jhaveri M, Chung H, Miller A. Healthcare utilization and costs of newly diagnosed multiple sclerosis using real-world data from a US managed care perspective. Academy of Managed Care Pharmacy’s (AMCP) Annual Meeting & Showcase Program, San Antonio 2008 (Poster Presentation).
  10. Ho E, Asche CV, Coyte PC, Chan B. The Economic Costs of Multiple Sclerosis in Canada Multiple Sclerosis. 1997 (Podium Presentation).